2 issues I've noticed on 3.5.3 with iOS6.0.1
1) When driving and it finds a better route, it has the new ETA and old ETA values reversed. The status bar on the bottom of the screen shows the new ETA and the popup window shows the old ETA, with the tag that says 'new ETA'.
2) When choosing a destination, I can find the location and it picks a route. The window that displays with the mileage and ETA, along with the 'Go' button will freeze. The countdown timer on the 'Go' button doesn't move and it will show the spinning Waze icon in the center of the screen. I have to hit the home button to leave the app, then when I restart Waze it will crash, then I can restart again successfully.
Debug logs for both of these issues have been submitted.