On my Garmin which I no longer use since I started using Waze would use a lane assist in the top left hand corner of the GPS. Say you are on a route with multiple exits and lanes. The lane you should be in was highlighted. This helped big time so I was in the correct lane without making a late change.

In Philly especially on 76 near Center City many of the off ramps seem to run together and I miss much more frequently than I care to admit. Sometimes it's better to get off instead of missing but a few it literally takes 10 minutes to get back on the correct route if I get off the route early.