Here is a link to MO-DOT’s website. You will find a PDF version (a front of map PDF and a separate back of map PDF).
Please note that if you are a state resident you can use this website to request a free paper copy!
nice find. MO Dot has some good info on their road and intersection updates.
I have some really good resources at my county planning and zoning and assessor’s office so if anything needs to be clarified in Greene County, I can do it! 
EW Gateway makes the entire 8 county St Louis Metro region available as 6" resolution aerial photos flown in 2012:
http://www.ewgateway.org/gis/2012AIFactSheet.pdf
Even without GIS software, you can view the entire set here:
http://moimagery.missouri.edu/arcgis/rest/services/LGov/EWGateway2012_6inch/ImageServer?f=jsapi
You can also go here:
http://www.arcgis.com/home/webmap/viewer.html?useExisting=1
Click Add, then Add Layer from Web and enter:
http://moimagery.missouri.edu/arcgis/rest/services/LGov/EWGateway2012_6inch/ImageServer
After a few seconds, the 2012 imagery will be added to the map. You can toggle it on or off or set transparency with the other basemaps (bing, OSM, Esri) available there.
Copying this post over from the main US forum too:
State of Missouri spatial data clearinghouse:
http://msdis.missouri.edu/
This is the download link for every transportation file provided by the state:
ftp://msdis.missouri.edu/pub/state/transportation/st_trans06.e00.zip
But you are better off going here first and toggling on the transportation layers:
http://www.msdis.missouri.edu/data/themelist.html
They also have webservices:
http://msdis.missouri.edu/webservices/mapping/index.html
This is every road in the state cataloged by MoDOT as an ArcGIS REST endpoint:
http://msdisweb.missouri.edu/ArcGIS/rest/services/MoDOT_Roads_Quarterly_December_2012_WMS/MapServer
And as a KML generator REST endpoint:
http://msdisweb.missouri.edu/ArcGIS/rest/services/MoDOT_Roads_Quarterly_December_2012_WMS/MapServer/generatekml
These are ArcGIS REST endpoints for every quarterly updated of the roads layers:
http://msdisweb.missouri.edu/ArcGIS/rest/services/MSDIS_Download/MapServer/182
Excellent! Thank you marigolds!!!
Here’s another excellent resource, MODOT’s weekly report:
http://www.modot.org/stlouis/road_construction/weeklyupdate.htm
This will help you when mapping construction zones and helping to edit the map to route around road closures that last more than a few days (think long term projects).
MODOT KC District Functional Classification Maps:
Jackson County GIS:
A few St. Louis area resources
St. Charles County GIS: http://map.sccmo.org/Main/
St. Louis County GIS: http://maps.stlouisco.com/propertyview/
St. Louis City: http://stlcin.missouri.org/citydata/newdesign/map.cfm
We started maintaining a map of roads closed due to flooding, based on information from county highways:
http://www.arcgis.com/home/webmap/viewer.html?webmap=3efdf4bb6ad74e919cdc04f389e9f272
Submitted the flooding as an MTE, but if someone can edit this in as closures that would be very helpful!
We update every morning.
Thank you for the closure map. It’s really helpful.
Here’s an interactive Kansas City MO GIS map. Very Helpful for street names and parcel addresses.
Kansas City District MoDOT daily closures.
http://maps.hornershifrin.com/henrycountymo/ Henry Co. GIS map